You or someone you love has been diagnosed with an aggressive form of cancer.

Conventional medicine — the “standard of care” — offers little or no hope.

The Jaime Leandro Foundation does.

Personalized Neoantigen Vaccines through Expanded Access

Traditional vaccines revolutionized the treatment of disease. In recent years, personalized vaccines have shown promise in combating cancer. At the same time, technological advances have become more accessible, and the FDA introduced “Expanded Access” which gives an individual the right to try a medical treatment when no comparable alternative options are available.

JLF and partners allowed us the option to pursue a treatment we wanted, a cancer therapy based on current research, trials, and science.” said Brad C. Through cancer vaccines, we now have hope for more time, better chance for survival, and hopefully a roadmap for others to follow as well.
— Brad C., husband of JLF patient

The Jaime Leandro Foundation for Therapeutic Cancer Vaccines (JLF) is a private nonprofit organization established to deliver breakthrough cancer treatments based on the latest innovations in research and personalized medicine and leveraging the Expanded Access rule — also known as “Compassionate Use.” We bring the critical components together, partnering with expert academic and commercial institutions to develop and deliver therapeutic vaccines personalized for each patient.

In essence, JLF is the hub, and our partners use advanced genetic sequencing, identify the best patient-specific neoantigen targets, and manufacture, assemble, vial, and ship the personalized vaccine, which is administered by the treating physician. Then, JLF partners monitor and report results for the advancement of knowledge overall.

JLF is led by experts in cancer, personalized medicine, clinical trials, and vaccines. Meet them here.


The JLF Process

The JLF process involves industry leaders providing cutting-edge technology at every step. Developing a personalized therapeutic vaccine takes approximately 4-5 months:

To learn specifics about the JLF process, timing, and costs, please see the FAQs.


Collaborators

Our partners are at the forefront of medicine and science. Each is an industry leader providing cutting-edge expertise and technology. JLF consults with the patient, coordinates with partners, and helps both navigate the entire process. CSBio, Ennov1, and xCures form the heart of the JLF consortium.